74.9 F
The Villages
Friday, September 23, 2022

Booster dose reduces COVID-19 transmission and infection

Dr. Gabe Mirkin

The initial, second and booster doses of the COVID-19 vaccines have been remarkably effective in reducing the disease’s infections, hospitalizations, intensive care admissions, intubations and deaths through the world (JAMA, Jan 25, 2022;327(4):327-328). The negative results of the vaccination programs are:
• lack of adequate vaccine distribution to everyone throughout the world
• unusual side effects of the vaccine in some people, but they are vastly less frequent than the number of lives saved by the vaccine
• unrealistically exaggerated fears of side effects from the vaccine by some people
• not getting vaccinated encourages the future emergence of variants that may partly resist vaccine-induced antibodies. Incomplete protection by the vaccine in some people with defective immunities causes them to carry the virus for prolonged periods that encourages more virus to be produced and increased risk for mutations that can become resistant to future vaccinations (mSphere, 2021;6(4):e0024421).

That same issue of the JAMA has an Israeli study showing a booster dose raises antibody titers higher and further reduces both symptomatic and asymptomatic COVID-19 infections (JAMA, Jan 25, 2022;327(4):341-349). The majority of health care workers who received two doses of the Pfizer vaccine had high protective blood antibody titers, but six months later, their protective antibody blood titers had lowered considerably. Some of the workers were given a third booster dose and were compared to workers who received only two doses of the vaccine. Those with a third booster dose were infected with the COVID-19 virus at a rate of 116 per 100,000 person-days prior to booster vaccination, compared to 2.8 per 100,000 after booster vaccination. That’s a relative reduction rate of 93 percent

The CDC now recommends a third booster dose six months after the two vaccine doses, preferably with an mRNA vaccine (Pfizer or Moderna). The U.S. Food and Drug Administration recommends a third dose of mRNA at least 5 months after the second dose for adolescents aged 12 to 15 years and for children aged 5 to 11 years who are immunocompromised.

Dr. Gabe Mirkin is a Villager. Learn more at www.drmirkin.com

More Headlines
Stories in and around The Villages, Florida

The Villages, Florida

Letters to the Editor
Opinions submitted by residents in and around The Villages

Rentals are great for big families visiting The Villages

A woman whose mother is a longtime resident of The Villages says that rentals are great when the family comes to town. Read her Letter to the Editor.

Free roofs are not free

A Village of DeLuna resident, in a Letter to the Editor, has a message for those who have gotten “free” roofs.

Gov. DeSantis standing up for election integrity

In a Letter to the Editor, a Village of Osceola Hills resident says she is proud that Gov. Ron DeSantis is standing up for election integrity.

It was an awfully expensive plane ride to Martha’s Vineyard

A Village of Virginia Trace resident asks where were the fiscal watchdogs when Gov. DeSantis spent $12,300 per migrant to fly them from Texas to Martha’s Vineyard?

Villager’s son wants answers about future of his mother’s retirement

A Villager’s son wants answers about the future of his mother’s retirement as short-term rentals have upset the balance of life in Florida’s Friendliest Hometown.

The Villages, Florida